SCHEMBL920445

SCHEMBL920445

Cc1ccccc1COc1ccc(CNC(=O)c2cccnc2N)cc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.49
LMNA P02545 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
MAPK1 P28482 1/20 0.49
MAPK8 P45983 1/20 0.47
MAOB P27338 1/20 0.47
POLB P06746 1/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
PIK3CD O00329 1/20 0.46
RORC P51449 1/20 0.46
EGLN1 Q9GZT9 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1680967 0.89 HDAC1 (0.51) HPGDLMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL920847 0.89 HPGD (0.52) HPGDKDM4EALDH1A1MAPK8POLB
SCHEMBL12943613 0.88 MAPK8 (0.48) HPGDLMNASMN1; SMN2MAPK8MEN1
SCHEMBL921387 0.88 RORC (0.61) HPGDLMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL1681273 0.87 SCN3A (0.56) HPGDLMNASMN1; SMN2MAPK8MAOB
SCHEMBL923290 0.87 MAPK8 (0.53) HPGDLMNASMN1; SMN2ALDH1A1MAPK8
SCHEMBL21580172 0.86 HPGD (0.62) HPGDLMNASMN1; SMN2MAPK1MAPK8
SCHEMBL922511 0.86 HPGD (0.60) HPGDLMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL922540 0.85 MAPK8 (0.58) HPGDLMNASMN1; SMN2MAPK8MEN1
SCHEMBL922058 0.84 MAPK8 (0.59) LMNASMN1; SMN2ALDH1A1MAPK8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885LMNA 4812/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.