SCHEMBL921387

SCHEMBL921387

COc1ccccc1COc1ccc(CNC(=O)c2cccnc2N)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.61
HPGD P15428 6/20 0.53
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 2/20 0.53
POLB P06746 2/20 0.53
RCE1 Q9Y256 1/20 0.53
MAPT P10636 3/20 0.53
LMNA P02545 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
PLA2G1B P04054 1/20 0.52
ATG4B Q9Y4P1 1/20 0.52
TP53 P04637 1/20 0.51
GLA P06280 1/20 0.51
TSHR P16473 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPK8 P45983 1/20 0.49
EGLN1 Q9GZT9 1/20 0.48
GAA P10253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921137 0.90 RORC (0.50) RORCHPGDALDH1A1KDM4EPOLB
SCHEMBL921619 0.89 HPGD (0.55) RORCHPGDALDH1A1KDM4EPOLB
SCHEMBL920445 0.88 HPGD (0.49) RORCHPGDALDH1A1KDM4EPOLB
SCHEMBL1680967 0.87 HDAC1 (0.51) RORCHPGDALDH1A1KDM4EMAPT
SCHEMBL12943613 0.86 MAPK8 (0.48) RORCHPGDMAPTLMNASMN1; SMN2
SCHEMBL921143 0.86 CARM1 (0.56) HPGDALDH1A1KDM4EPOLBMAPT
SCHEMBL921980 0.86 HPGD (0.64) HPGDALDH1A1POLBMAPTLMNA
SCHEMBL1681273 0.85 SCN3A (0.56) HPGDLMNASMN1; SMN2MEN1KMT2A
SCHEMBL923290 0.85 MAPK8 (0.53) HPGDALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL921981 0.85 HPGD (0.70) HPGDALDH1A1POLBMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 RORC 377/4885HPGD 1273/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.