SCHEMBL920465

SCHEMBL920465

C=CCCOc1ccc[c]c1F

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
HPGD P15428 2/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
KMT2A Q03164 1/20 0.34
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919216 0.92 KDM4E (0.38) KDM4EHPGDTSHRMAPK1HSD17B10
SCHEMBL921468 0.90 KDM4E (0.37) KDM4EHPGDTSHRMAPK1HSD17B10
SCHEMBL920371 0.89 ALDH1A1 (0.36) KDM4EHPGDTSHRMAPK1HSD17B10
SCHEMBL921324 0.83 HPGD (0.42) KDM4EHPGDTSHRMAPK1HSD17B10
SCHEMBL920608 0.81 L3MBTL1 (0.35) KDM4EL3MBTL1TDP1
SCHEMBL919428 0.81 L3MBTL1 (0.32) KDM4EMAPK1ALDH1A1L3MBTL1TDP1
SCHEMBL920610 0.81 L3MBTL1 (0.35) KDM4EL3MBTL1TDP1
SCHEMBL919430 0.81 L3MBTL1 (0.32) KDM4EMAPK1ALDH1A1L3MBTL1TDP1
SCHEMBL921344 0.80 L3MBTL1 (0.34) KDM4EL3MBTL1TDP1
SCHEMBL921343 0.80 L3MBTL1 (0.34) KDM4EL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 KDM4E 3657/4885HPGD 1273/4885TSHR 2588/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 KDM4E 3733/4885HPGD 1474/4885TSHR 2777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.