Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4406688 | 0.85 | NPSR1 (0.57) | NPSR1ALDH1A1MAPTHTTHPGD | |
| SCHEMBL9208359 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTHPGDLMNA | |
| SCHEMBL13294750 | 0.79 | ALDH1A1 (0.53) | NPSR1ALDH1A1MAPTHTTHPGD | |
| SCHEMBL27718591 | 0.75 | NPSR1 (0.46) | NPSR1ALDH1A1MAPTHTTHPGD | |
| Hydrochloric Acid SCHEMBL29943476 | 0.74 | ALDH1A1 (0.47) | NPSR1ALDH1A1MAPTHTTHPGD | |
| SCHEMBL10681004 | 0.74 | ALDH1A1 (0.44) | NPSR1ALDH1A1MAPTHTTHPGD | |
| SCHEMBL13344784 | 0.72 | ALDH1A1 (0.56) | NPSR1ALDH1A1MAPTHTTHPGD | |
| SCHEMBL9208351 | 0.72 | MCOLN2 (0.45) | NPSR1ALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL10681010 | 0.72 | NPSR1 (0.44) | NPSR1ALDH1A1MAPTHTTHPGD | |
| SCHEMBL16162343 | 0.72 | ALDH1A1 (0.65) | NPSR1ALDH1A1MAPTHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489877-B1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES | UPJOHN CO (US) | 1995-09-20 | — | — | EP | disclosed |