Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204700 | 0.82 | NPSR1 (0.54) | ALDH1A1L3MBTL1POLBTDP1LMNA | |
| SCHEMBL8616090 | 0.72 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1HSD11B1IDO1TDO2 | |
| SCHEMBL17768274 | 0.71 | HSD11B1 (0.55) | ALDH1A1L3MBTL1HSD11B1IDO1TDO2 | |
| SCHEMBL9208365 | 0.70 | HSD11B1 (0.64) | ALDH1A1L3MBTL1HSD11B1IDO1TDO2 | |
| SCHEMBL9380046 | 0.69 | ALDH1A1 (0.85) | ALDH1A1L3MBTL1HSD11B1GRM1CHRNB2 | |
| SCHEMBL8464852 | 0.69 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1HSD11B1IDO1TDO2 | |
| SCHEMBL4406688 | 0.68 | NPSR1 (0.57) | ALDH1A1L3MBTL1TDP1LMNATP53 | |
| SCHEMBL15284438 | 0.68 | NFE2L2 (0.41) | ALDH1A1L3MBTL1IDO1TDO2GRM1 | |
| SCHEMBL365218 | 0.67 | — | — | |
| SCHEMBL9208375 | 0.67 | HSD11B1 (0.64) | ALDH1A1L3MBTL1HSD11B1IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489877-B1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES | UPJOHN CO (US) | 1995-09-20 | — | — | EP | disclosed |