Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | F7 | P08709 | 4/20 | 0.49 |
| ▸ | F3 | P13726 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | FABP4 | P15090 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204706 | 1.00 | FAAH (0.53) | FAAHSOAT1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL8923210 | 0.85 | SOAT2 (0.59) | FAAHSOAT1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL1875392 | 0.79 | HSD17B3 (0.59) | FAAHSOAT1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9205011 | 0.76 | PSMB11 (0.78) | FAAHSOAT1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL3922002 | 0.76 | PSMB11 (0.78) | FAAHSOAT1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL21367188 | 0.76 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1LMNAFFAR1 | |
| Aminobenzoic Acid SCHEMBL11488167 | 0.76 | MAPT (0.53) | FAAHCYP1A2CYP2C19KMT2ATP53 | |
| SCHEMBL14722425 | 0.75 | CES2 (0.54) | KMT2AMEN1ALDH1A1PPARGPPARD | |
| SCHEMBL21357337 | 0.74 | TP53 (0.53) | KMT2AMEN1TP53ALDH1A1TSHR | |
| Aminobenzoic Acid SCHEMBL11486804 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1TP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |