Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210338 | 0.92 | ACHE (0.52) | ACHEMCHR1ALDH1A1MAPT | |
| SCHEMBL9206779 | 0.84 | ACHE (0.57) | ACHE | |
| SCHEMBL9206324 | 0.83 | ACHE (0.58) | ACHE | |
| SCHEMBL9208669 | 0.82 | ALDH1A1 (0.59) | ACHEALDH1A1MAPT | |
| SCHEMBL9206611 | 0.81 | ACHE (0.70) | ACHEMCHR1 | |
| SCHEMBL7227822 | 0.80 | MCHR1 (0.55) | ACHEMCHR1 | |
| SCHEMBL9210160 | 0.78 | ACHE (0.69) | ACHEMCHR1ALDH1A1 | |
| SCHEMBL7226505 | 0.76 | MCHR1 (0.52) | ACHEMCHR1 | |
| SCHEMBL9208257 | 0.76 | ACHE (0.70) | ACHEMCHR1ALDH1A1 | |
| SCHEMBL9208181 | 0.76 | ACHE (0.57) | ACHEALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487071-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-07-05 | — | — | EP | disclosed |
| US-5273974-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-28 | — | — | US | disclosed |
| EP-0487071-A1 | Condensed heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |