Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 1/20 | 0.47 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210225 | 0.91 | CHIA (0.46) | CHIALSSL3MBTL3LMNAMCHR1 | |
| SCHEMBL9209385 | 0.91 | LSS (0.50) | LSSPOLBL3MBTL3MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9210051 | 0.87 | L3MBTL3 (0.39) | CHIT1CHIALSSL3MBTL3 | |
| SCHEMBL9207092 | 0.86 | PIK3CA (0.45) | L3MBTL3MCHR1 | |
| Hydrochloric Acid SCHEMBL9211396 | 0.84 | MCHR1 (0.47) | LSSL3MBTL3MCHR1 | |
| SCHEMBL9208974 | 0.84 | CHIA (0.40) | CHIALSSL3MBTL3MGLL | |
| Hydrochloric Acid SCHEMBL9203024 | 0.82 | ALDH1A1 (0.44) | POLBL3MBTL3MAPTALDH1A1MCHR1 | |
| Hydrochloric Acid SCHEMBL9205634 | 0.80 | CHIA (0.43) | CHIAMGLLNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9203459 | 0.80 | CHIA (0.43) | CHIALSSPOLBL3MBTL3LMNA | |
| Hydrochloric Acid SCHEMBL9209408 | 0.80 | CHIA (0.44) | CHIALSSL3MBTL3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |