Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 6/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210225 | 0.89 | CHIA (0.46) | CHIAL3MBTL3LSSABL1HDAC4 | |
| SCHEMBL9205608 | 0.84 | CHIT1 (0.47) | CHIAL3MBTL3LSSMGLL | |
| Hydrochloric Acid SCHEMBL9211396 | 0.83 | MCHR1 (0.47) | L3MBTL3LSSHRH3HTR2B | |
| Hydrochloric Acid SCHEMBL9205634 | 0.82 | CHIA (0.43) | CHIAATRABL1HRH3MGLL | |
| Hydrochloric Acid SCHEMBL9203459 | 0.81 | CHIA (0.43) | CHIAL3MBTL3LSSABL1HRH3 | |
| Hydrochloric Acid SCHEMBL9203024 | 0.81 | ALDH1A1 (0.44) | L3MBTL3HTR2B | |
| Hydrochloric Acid SCHEMBL9202408 | 0.80 | CHIA (0.45) | CHIAL3MBTL3ABL1 | |
| Hydrochloric Acid SCHEMBL9210051 | 0.80 | L3MBTL3 (0.39) | CHIAL3MBTL3LSSHDAC4HRH3 | |
| SCHEMBL9207092 | 0.80 | PIK3CA (0.45) | L3MBTL3ATRABL1HRH3 | |
| SCHEMBL9209529 | 0.79 | CHIA (0.43) | CHIAL3MBTL3ABL1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |