SCHEMBL9209385

SCHEMBL9209385

CN(Cc1ccc(Cl)cc1)C1CCN(C(=O)c2ccc(-c3nc[nH]n3)cc2)CC1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LSS P48449 2/20 0.50
L3MBTL3 Q96JM7 1/20 0.44
MAPT P10636 3/20 0.43
ALDH1A1 P00352 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
LMNA P02545 1/20 0.43
HPGD P15428 1/20 0.43
HSD11B1 P28845 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MGLL Q99685 5/20 0.41
POLB P06746 1/20 0.41
HDAC4 P56524 1/20 0.41
HRH3 Q9Y5N1 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9205608 0.91 CHIT1 (0.47) LSSL3MBTL3MAPTALDH1A1NPC1
SCHEMBL9210225 0.81 CHIA (0.46) LSSL3MBTL3LMNAHDAC4HRH3
Hydrochloric Acid SCHEMBL9211396 0.79 MCHR1 (0.47) LSSL3MBTL3HRH3
Hydrochloric Acid SCHEMBL9210051 0.78 L3MBTL3 (0.39) LSSL3MBTL3HDAC4HRH3
SCHEMBL9207092 0.77 PIK3CA (0.45) L3MBTL3HRH3
SCHEMBL9208974 0.77 CHIA (0.40) LSSL3MBTL3MGLLHDAC4HRH3
Hydrochloric Acid SCHEMBL9203024 0.76 ALDH1A1 (0.44) L3MBTL3MAPTALDH1A1POLB
SCHEMBL7471244 0.76 LSS (0.51) LSSL3MBTL3MAPTALDH1A1LMNA
SCHEMBL9207587 0.74 SMN1; SMN2 (0.45) L3MBTL3SMN1; SMN2
SCHEMBL9209625 0.74 PIK3R1 (0.50) L3MBTL3ALDH1A1LMNAHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0650476-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-05-03 EP disclosed