SCHEMBL921092

SCHEMBL921092

Cc1ccc(Oc2cccc(CNC(=O)c3cccnc3N)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 2/20 0.58
HPGD P15428 5/20 0.54
KMT2A Q03164 1/20 0.54
MAPK8 P45983 1/20 0.53
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 2/20 0.52
USP2 O75604 1/20 0.52
GAA P10253 1/20 0.50
PPARG P37231 2/20 0.49
PPARD Q03181 2/20 0.49
PPARA Q07869 2/20 0.49
MAPK14 Q16539 1/20 0.49
HSD17B10 Q99714 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920078 0.93 HPGD (0.56) MMP13HPGDKMT2AMAPK8KDM4E
SCHEMBL920077 0.92 HPGD (0.62) MMP13HPGDKMT2AMAPK8KDM4E
SCHEMBL920497 0.92 HPGD (0.54) MMP13HPGDKMT2AMAPK8KDM4E
SCHEMBL1680406 0.91 MAPK8 (0.63) HPGDKMT2AMAPK8KDM4EALDH1A1
SCHEMBL919694 0.91 HPGD (0.61) HPGDKMT2AMAPK8KDM4EALDH1A1
SCHEMBL920562 0.91 HPGD (0.56) MMP13HPGDKMT2AMAPK8KDM4E
SCHEMBL922484 0.90 HPGD (0.62) MMP13HPGDMAPK8KDM4EALDH1A1
SCHEMBL920714 0.89 MAPK8 (0.53) HPGDKMT2AMAPK8KDM4EALDH1A1
SCHEMBL921549 0.89 MAPK8 (0.53) MMP13HPGDKMT2AMAPK8KDM4E
SCHEMBL920985 0.89 MAPK8 (0.53) MMP13HPGDKMT2AMAPK8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MMP13 4062/4885HPGD 1273/4885KMT2A 2469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.