SCHEMBL920568

SCHEMBL920568

COc1ccc(Oc2cccc(CNC(=O)c3ccc(C)nc3N)c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 2/20 0.57
HPGD P15428 2/20 0.56
KDM4E B2RXH2 2/20 0.56
ALDH1A1 P00352 2/20 0.56
USP2 O75604 1/20 0.56
CHRM4 P08173 3/20 0.53
PPARG P37231 2/20 0.53
PPARA Q07869 2/20 0.53
PPARD Q03181 1/20 0.53
ROCK2 O75116 1/20 0.51
ROCK1 Q13464 1/20 0.51
APEX1 P27695 1/20 0.50
RAB9A P51151 1/20 0.49
FLT1 P17948 1/20 0.48
LRRK2 Q5S007 1/20 0.48
KMT2A Q03164 1/20 0.48
TP53 P04637 2/20 0.48
LMNA P02545 1/20 0.48
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920306 0.95 HPGD (0.60) MMP13HPGDKDM4EALDH1A1USP2
SCHEMBL921580 0.93 MMP13 (0.58) MMP13HPGDKDM4EALDH1A1USP2
SCHEMBL920750 0.93 KDM4E (0.54) MMP13HPGDKDM4EALDH1A1USP2
SCHEMBL921494 0.92 HPGD (0.65) MMP13HPGDKDM4EALDH1A1USP2
SCHEMBL920890 0.92 MMP13 (0.52) MMP13HPGDKDM4EALDH1A1USP2
SCHEMBL920119 0.91 PPARG (0.53) MMP13HPGDKDM4EALDH1A1USP2
SCHEMBL919826 0.91 MMP13 (0.48) MMP13HPGDKDM4EALDH1A1USP2
SCHEMBL921419 0.91 MMP13 (0.48) MMP13HPGDKDM4EALDH1A1USP2
SCHEMBL921861 0.91 MMP13 (0.48) MMP13HPGDKDM4EALDH1A1USP2
SCHEMBL922174 0.89 KDM4E (0.53) MMP13HPGDKDM4EALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MMP13 4062/4885HPGD 1273/4885KDM4E 3657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.