SCHEMBL920607

SCHEMBL920607

Cc1cccc(Oc2cc[c]c(F)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
ACHE P22303 2/20 0.46
HTT P42858 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
GAA P10253 1/20 0.44
AR P10275 3/20 0.42
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
LYN P07948 1/20 0.41
LMNA P02545 3/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
F2 P00734 1/20 0.37
GFER P55789 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919676 0.83 SMN1; SMN2 (0.50) ALDH1A1ACHEL3MBTL1MEN1KMT2A
SCHEMBL920492 0.82 TEAD4 (0.44) ALDH1A1ACHEHTTL3MBTL1TDP1
SCHEMBL919927 0.82 SLC6A2 (0.38) ALDH1A1KMT2AMAPT
SCHEMBL920762 0.82 LTA4H (0.48) ALDH1A1HTTGAAMEN1KMT2A
SCHEMBL922603 0.79 AR (0.42) HTTARLMNAKMT2ASMN1; SMN2
SCHEMBL29398372 0.79 ALDH1A1 (0.72) ALDH1A1ACHEHTTL3MBTL1TDP1
SCHEMBL456868 0.79 ALDH1A1 (0.72) ALDH1A1ACHEHTTL3MBTL1TDP1
SCHEMBL29746015 0.79 ALDH1A1 (0.72) ALDH1A1ACHEHTTL3MBTL1TDP1
SCHEMBL921452 0.78 ALDH1A1 (0.61) ALDH1A1ACHEHTTL3MBTL1TDP1
SCHEMBL29377828 0.77 ALDH1A1 (0.69) ALDH1A1ACHEHTTL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ALDH1A1 2743/4885ACHE 3081/4885HTT 2561/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 ALDH1A1 4326/4885ACHE 4121/4885HTT 450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.