Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 4/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204541 | 1.00 | LMNA (0.41) | LMNADNM1TSHRTHRBCA2 | |
| SCHEMBL9209590 | 1.00 | LMNA (0.41) | LMNADNM1TSHRTHRBCA2 | |
| SCHEMBL9212808 | 1.00 | LMNA (0.41) | LMNADNM1TSHRTHRBCA2 | |
| SCHEMBL9204961 | 1.00 | LMNA (0.41) | LMNADNM1TSHRTHRBCA2 | |
| SCHEMBL9211948 | 1.00 | LMNA (0.41) | LMNADNM1TSHRTHRBCA2 | |
| SCHEMBL9207568 | 1.00 | LMNA (0.41) | LMNADNM1TSHRTHRBCA2 | |
| SCHEMBL7055552 | 0.97 | OPRM1 (0.40) | LMNADNM1TSHRTHRBCA2 | |
| SCHEMBL6050218 | 0.90 | DNM1 (0.38) | LMNADNM1TSHRCA2OPRM1 | |
| SCHEMBL5933050 | 0.78 | — | — | |
| SCHEMBL19123662 | 0.74 | FDPS (0.48) | LMNADNM1TSHRTHRBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |