Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210022 | 0.85 | MAPT (0.52) | POLBKMT2ASMN1; SMN2MAPTTP53 | |
| SCHEMBL8434365 | 0.85 | MAPT (0.52) | POLBKMT2ASMN1; SMN2MAPTTP53 | |
| SCHEMBL9209938 | 0.82 | RECQL (0.48) | POLBKMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8434038 | 0.80 | ALDH1A1 (0.44) | POLBKMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL9206350 | 0.79 | FGFR4 (0.47) | POLBKMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL9211250 | 0.77 | KMT2A (0.40) | POLBKMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL9211256 | 0.77 | KMT2A (0.40) | POLBKMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL9210053 | 0.75 | SLC6A9 (0.47) | POLBKMT2AMAPTGAAALDH1A1 | |
| SCHEMBL9207012 | 0.75 | SLC6A9 (0.47) | POLBKMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL4539912 | 0.74 | KMT2A (0.50) | POLBKMT2ASMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544218-B1 | Arylindazole derivatives and their use | SUMITOMO CHEMICAL CO (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5266556-A | Herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-30 | — | — | US | disclosed |
| EP-0544218-A1 | Arylindazole derivatives and their use | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-06-02 | — | — | EP | disclosed |