SCHEMBL9207012

SCHEMBL9207012

O=[N+]([O-])c1ccc2cnn(-c3ncc(C(F)(F)F)cc3Cl)c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 1/20 0.47
FGFR4 P22455 1/20 0.43
KMT2A Q03164 2/20 0.42
GAA P10253 3/20 0.42
HSD11B1 P28845 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
RECQL P46063 1/20 0.41
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 4/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9210053 0.91 SLC6A9 (0.47) SLC6A9FGFR4KMT2AGAAHSD11B1
SCHEMBL9206083 0.85 MAPT (0.40) SLC6A9FGFR4KMT2AALDH1A1MAPT
SCHEMBL9206350 0.84 FGFR4 (0.47) FGFR4KMT2AGAAHSD11B1ATM
SCHEMBL8434365 0.80 MAPT (0.52) KMT2AGAAHSD11B1ATML3MBTL1
SCHEMBL8434038 0.80 ALDH1A1 (0.44) KMT2AGAAHSD11B1ATML3MBTL1
SCHEMBL9558744 0.78 ALDH1A1 (0.47) SLC6A9FGFR4KMT2AGAARECQL
SCHEMBL19533519 0.76 GLS (0.38) KMT2AALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL9207202 0.75 POLB (0.45) KMT2AGAAATML3MBTL1RECQL
SCHEMBL9209938 0.75 RECQL (0.48) KMT2AGAAATML3MBTL1RECQL
SCHEMBL6951629 0.74 FGFR4 (0.46) FGFR4KMT2AGAAATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544218-B1 Arylindazole derivatives and their use SUMITOMO CHEMICAL CO (JP) 1995-07-26 EP disclosed
US-5266556-A Herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-30 US disclosed
EP-0544218-A1 Arylindazole derivatives and their use SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-06-02 EP disclosed