SCHEMBL9209938

SCHEMBL9209938

FC(F)(F)c1cnc(-n2ncc3cc(Cl)ccc32)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.48
CYP11B1 P15538 2/20 0.45
CYP11B2 P19099 2/20 0.45
CNR2 P34972 1/20 0.45
POLB P06746 1/20 0.45
KMT2A Q03164 2/20 0.45
GAA P10253 2/20 0.45
ATM Q13315 1/20 0.44
LMNA P02545 1/20 0.43
XBP1 P17861 1/20 0.43
PPARG P37231 1/20 0.43
HTT P42858 1/20 0.43
NCOA2 Q15596 1/20 0.43
NCOA1 Q15788 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43
NR3C1 P04150 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9210022 0.87 MAPT (0.52) RECQLCYP11B1CYP11B2POLBKMT2A
SCHEMBL9210053 0.82 SLC6A9 (0.47) RECQLCYP11B1CYP11B2POLBKMT2A
SCHEMBL9207202 0.82 POLB (0.45) RECQLPOLBKMT2AGAAATM
SCHEMBL8434365 0.80 MAPT (0.52) RECQLPOLBKMT2AGAAATM
SCHEMBL8434038 0.80 ALDH1A1 (0.44) RECQLCYP11B2POLBKMT2AGAA
SCHEMBL13844031 0.77 TDP1 (0.43) RECQLCNR2KMT2AGAAATM
SCHEMBL9206350 0.77 FGFR4 (0.47) RECQLCNR2POLBKMT2AGAA
SCHEMBL9207012 0.75 SLC6A9 (0.47) RECQLPOLBKMT2AGAAATM
SCHEMBL9211250 0.75 KMT2A (0.40) RECQLPOLBKMT2AGAAATM
SCHEMBL9211256 0.75 KMT2A (0.40) RECQLPOLBKMT2AGAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544218-B1 Arylindazole derivatives and their use SUMITOMO CHEMICAL CO (JP) 1995-07-26 EP disclosed
US-5266556-A Herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-30 US disclosed
EP-0544218-A1 Arylindazole derivatives and their use SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-06-02 EP disclosed