Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14623987 | 0.94 | ALDH1A1 (0.37) | ALDH1A1KDM4EEPHX1DNM1TSHR | |
| SCHEMBL19901772 | 0.86 | KDM4E (0.37) | ALDH1A1KDM4EEPHX1DNM1TSHR | |
| SCHEMBL28255157 | 0.81 | ALDH1A1 (0.37) | ALDH1A1DNM1TSHRCYP3A4 | |
| Bromide SCHEMBL7940382 | 0.78 | DNM1 (0.43) | ALDH1A1KDM4EEPHX1DNM1TSHR | |
| SCHEMBL24632181 | 0.75 | LMNA (0.37) | EPHX1DNM1TSHRADH1BADH1C | |
| SCHEMBL27427558 | 0.75 | DNM1 (0.36) | ALDH1A1KDM4EEPHX1DNM1TSHR | |
| SCHEMBL13824584 | 0.74 | DNM1 (0.37) | ALDH1A1KDM4EEPHX1DNM1TSHR | |
| SCHEMBL20751513 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KDM4EEPHX1TSHRADH1B | |
| SCHEMBL11222818 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KDM4EEPHX1TSHRADH1B | |
| SCHEMBL29286411 | 0.73 | SPHK1 (0.41) | ALDH1A1KDM4EEPHX1TSHRADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |