Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14623987 | 0.88 | ALDH1A1 (0.37) | KDM4EALDH1A1LMNASLC2A1EPHX1 | |
| SCHEMBL9207449 | 0.86 | ALDH1A1 (0.39) | KDM4EALDH1A1EPHX1DNM1ADH1B | |
| SCHEMBL27427558 | 0.85 | DNM1 (0.36) | KDM4EALDH1A1LMNASLC2A1EPHX1 | |
| SCHEMBL14679361 | 0.78 | LMNA (0.38) | LMNAEPHX1DNM1ADH1BADH1C | |
| SCHEMBL11252411 | 0.77 | ADH1B (0.39) | KDM4EALDH1A1LMNASLC2A1EPHX1 | |
| SCHEMBL9407565 | 0.75 | TSHR (0.37) | ALDH1A1TSHR | |
| SCHEMBL9205945 | 0.74 | EPHX1 (0.42) | KDM4ELMNASLC2A1EPHX1DNM1 | |
| SCHEMBL117250 | 0.74 | EPHX1 (0.42) | KDM4ELMNASLC2A1EPHX1DNM1 | |
| SCHEMBL25560568 | 0.74 | EPHX1 (0.42) | KDM4ELMNASLC2A1EPHX1DNM1 | |
| SCHEMBL9213526 | 0.74 | EPHX1 (0.42) | KDM4ELMNASLC2A1EPHX1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902703-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2018-02-27 | — | — | US | disclosed |