Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA2 | P00918 | 6/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258845 | 0.77 | USP30 (0.36) | CA1CA2CA9KMT2ALMNA | |
| SCHEMBL9214487 | 0.76 | ALDH1A1 (0.34) | FTOCA1CA2CA9MAPK1 | |
| SCHEMBL578900 | 0.75 | CHRNA7 (0.49) | FTOCA1CA2CA9MAPK1 | |
| SCHEMBL30325110 | 0.75 | P2RX7 (0.39) | HIF1AHSD17B10CYP2C19 | |
| SCHEMBL29240503 | 0.75 | P2RX7 (0.39) | HIF1AHSD17B10CYP2C19 | |
| SCHEMBL29240506 | 0.75 | P2RX7 (0.39) | HIF1AHSD17B10CYP2C19 | |
| SCHEMBL30324716 | 0.75 | P2RX7 (0.39) | HIF1AHSD17B10CYP2C19 | |
| SCHEMBL10362360 | 0.72 | CHRNA7 (0.41) | FTOCA1CA2CA9MAPK1 | |
| SCHEMBL7455324 | 0.71 | HCRTR1 (0.34) | CYP1A2KDM4ECYP2C19 | |
| SCHEMBL8537341 | 0.70 | FTO (0.49) | FTOCA1CA2CA9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | disclosed |