Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520632 | 1.00 | RAB9A (0.41) | RAB9ANPC1ALDH1A1MAPTHPGD | |
| SCHEMBL9519253 | 0.92 | ALDH1A1 (0.39) | RAB9ANPC1ALDH1A1MAPTHPGD | |
| SCHEMBL9519895 | 0.92 | TDP1 (0.42) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL9020497 | 0.92 | RAB9A (0.40) | RAB9ANPC1ALDH1A1MAPTHPGD | |
| SCHEMBL9195878 | 0.91 | RAB9A (0.41) | RAB9ANPC1ALDH1A1MAPTHPGD | |
| SCHEMBL10513485 | 0.91 | TDP1 (0.41) | RAB9AALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8436015 | 0.91 | TDP1 (0.41) | RAB9AALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9520375 | 0.91 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL10513490 | 0.91 | TDP1 (0.41) | RAB9AALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8436018 | 0.91 | TDP1 (0.41) | RAB9AALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126587-B1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMA (JP) | 1995-04-19 | — | — | EP | disclosed |