Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519895 | 0.93 | TDP1 (0.42) | ALDH1A1MAOBMAPTHPGDTDP1 | |
| SCHEMBL8436018 | 0.92 | TDP1 (0.41) | ALDH1A1MAOBMAPTHPGDTDP1 | |
| SCHEMBL10513490 | 0.92 | TDP1 (0.41) | ALDH1A1MAOBMAPTHPGDTDP1 | |
| SCHEMBL8436015 | 0.92 | TDP1 (0.41) | ALDH1A1MAOBMAPTHPGDTDP1 | |
| SCHEMBL10513485 | 0.92 | TDP1 (0.41) | ALDH1A1MAOBMAPTHPGDTDP1 | |
| SCHEMBL9207906 | 0.91 | RAB9A (0.41) | ALDH1A1MAOBMAPTHPGDTDP1 | |
| SCHEMBL9520632 | 0.91 | RAB9A (0.41) | ALDH1A1MAOBMAPTHPGDTDP1 | |
| SCHEMBL7807884 | 0.90 | MMP2 (0.45) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL9043536 | 0.90 | TDP1 (0.40) | ALDH1A1MAOBMAPTHPGDTDP1 | |
| SCHEMBL9266276 | 0.89 | ALDH1A1 (0.39) | ALDH1A1MAOBMAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272455-B1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-10 | — | — | EP | disclosed |
| US-5138064-A | Chemical intermediate for penicillin derivative | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-4921852-A | CARBAPENICILLINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0272455-A1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |