SCHEMBL920795

SCHEMBL920795

N#Cc1ccccc1COc1cc[c]c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.46
FFAR1 O14842 1/20 0.45
SPHK2 Q9NRA0 2/20 0.39
SPHK1 Q9NYA1 1/20 0.39
ALKBH1 Q13686 1/20 0.39
PLAU P00749 1/20 0.39
KCNH2 Q12809 1/20 0.38
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ADAMTS4 O75173 1/20 0.36
MMP13 P45452 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921994 0.81 MAOB (0.50) MAOBNPC1RAB9AKDM4E
SCHEMBL920681 0.81 FFAR1 (0.56) MAOBFFAR1SPHK2ALKBH1PLAU
SCHEMBL920923 0.78 NR4A2 (0.49) MAOBKMT2AMEN1NPC1RAB9A
SCHEMBL921406 0.78 CDK4 (0.46) MAOBFFAR1SPHK2SPHK1KMT2A
SCHEMBL921217 0.76 PARP10 (0.53) MAOBSPHK2SPHK1KMT2AALDH1A1
SCHEMBL919896 0.75 POLB (0.50)
SCHEMBL9270379 0.75 FFAR1 (0.64) MAOBFFAR1SPHK2SPHK1ALKBH1
SCHEMBL5613168 0.75 MAOB (0.54) MAOBFFAR1SPHK2SPHK1ALKBH1
SCHEMBL919526 0.74 MAOB (0.51) MAOBSPHK2RAB9A
SCHEMBL920621 0.74 ALOX5 (0.51) MAOBKMT2AMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAOB 3730/4885FFAR1 3411/4885SPHK2 2574/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 MAOB 4351/4885FFAR1 2357/4885SPHK2 4273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.