SCHEMBL920799

SCHEMBL920799

COCc1ccc(C(=O)NCc2ccc(Oc3ccc(C(F)(F)F)c(F)c3)cc2)c(N)n1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.42
PPARD Q03181 4/20 0.42
PPARA Q07869 4/20 0.42
RECQL P46063 1/20 0.39
HCRTR1 O43613 1/20 0.39
HCRTR2 O43614 1/20 0.39
PTGES O14684 2/20 0.39
MAPK14 Q16539 1/20 0.39
MAPK1 P28482 1/20 0.38
CHRNA7 P36544 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
POLB P06746 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
KLKB1 P03952 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919842 0.93 PTPN7 (0.40) PPARGPPARDPPARARECQLPTGES
SCHEMBL922456 0.88 PPARD (0.42) PPARGPPARDPPARAMAPK1LIPG
SCHEMBL921283 0.87 PPARG (0.42) PPARGPPARDPPARAHCRTR1HCRTR2
SCHEMBL921417 0.87 MAPK14 (0.43) PPARGPPARDPPARAHCRTR1HCRTR2
SCHEMBL920005 0.87 MAPK14 (0.53) PPARGPPARDPPARARECQLMAPK14
SCHEMBL921868 0.86 PPARD (0.40) PPARGPPARDPPARAMAPK14MAPK1
SCHEMBL920779 0.86 LIPG (0.51) PPARGPPARDPPARAMAPK14LIPG
SCHEMBL920726 0.86 RECQL (0.51) PPARGPPARDPPARARECQLMAPK14
SCHEMBL921528 0.85 EPHX2 (0.47) PPARGPPARDPPARAMAPK14LIPG
SCHEMBL920422 0.85 PPARA (0.43) PPARGPPARDPPARARECQLMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 PPARG 391/4885PPARD 360/4885PPARA 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.