SCHEMBL920779

SCHEMBL920779

COCc1ccc(C(=O)NCc2ccc(Oc3ccc(F)cc3)cc2)c(N)n1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 2/20 0.51
CYP3A4 P08684 1/20 0.48
MAPK14 Q16539 1/20 0.48
POLB P06746 2/20 0.48
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46
MAPT P10636 3/20 0.46
THRB P10828 1/20 0.46
PTGER4 P35408 5/20 0.46
PTGER2 P43116 2/20 0.46
SCN9A Q15858 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1680793 0.92 MAPT (0.48) POLBPPARAMAPTTHRBSMN1; SMN2
SCHEMBL922841 0.91 EGLN1 (0.49) SMN1; SMN2LMNAL3MBTL1
SCHEMBL919997 0.90 MAPK14 (0.50) LIPGCYP3A4MAPK14PPARGPPARD
SCHEMBL920018 0.90 TP53 (0.41) LIPGCYP3A4MAPK14POLBPPARG
SCHEMBL922079 0.90 MAPK14 (0.50) CYP3A4MAPK14MAPTHTTSMN1; SMN2
SCHEMBL920083 0.90 HTR2C (0.45) LIPGPOLBPPARGPPARDPPARA
SCHEMBL920127 0.90 KDM4E (0.47) LIPGMAPK14PPARGPPARDPPARA
SCHEMBL920880 0.89 EGLN1 (0.41) LIPGCYP3A4MAPK14MAPTTHRB
SCHEMBL921652 0.89 AKR1B1 (0.41) LIPGCYP3A4MAPK14HTTSMN1; SMN2
SCHEMBL920636 0.89 CYP3A4 (0.48) CYP3A4MAPK14MAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 LIPG 3664/4885CYP3A4 3076/4885MAPK14 905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.