SCHEMBL920800

SCHEMBL920800

CCCCc1ccc(Oc2ccc(CNC(=O)c3ccc(COC)nc3N)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
CYSLTR1 Q9Y271 1/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
EGLN1 Q9GZT9 1/20 0.39
TRPV1 Q8NER1 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 2/20 0.38
PPARG P37231 1/20 0.38
PPARD Q03181 1/20 0.38
PPARA Q07869 1/20 0.38
KMT2A Q03164 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
MAPK14 Q16539 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921603 0.97 TRPV1 (0.42) LMNACYSLTR1GAAHTTEGLN1
SCHEMBL921221 0.95 TRPV1 (0.42) LMNACYSLTR1GAAHTTEGLN1
SCHEMBL920715 0.94 EGLN1 (0.40) LMNAHTTEGLN1SMN1; SMN2HPGD
SCHEMBL920719 0.92 SMN1; SMN2 (0.47) LMNAEGLN1SMN1; SMN2HPGD
SCHEMBL921404 0.92 ALDH1A1 (0.42) GAAHPGDPPARGPPARDPPARA
SCHEMBL921893 0.92 TRPV1 (0.46) LMNACYSLTR1GAATRPV1SMN1; SMN2
SCHEMBL920222 0.91 TRPV1 (0.45) LMNAGAATRPV1SMN1; SMN2HPGD
SCHEMBL920018 0.90 TP53 (0.41) LMNAHTTEGLN1SMN1; SMN2HPGD
SCHEMBL919883 0.89 KDM4E (0.41) TRPV1HPGDPPARGPPARDPPARA
SCHEMBL1680924 0.89 SMN1; SMN2 (0.50) LMNAEGLN1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 LMNA 4812/4885CYSLTR1 2363/4885GAA 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.