SCHEMBL920719

SCHEMBL920719

CCCCOc1ccc(Oc2ccc(CNC(=O)c3ccc(COC)nc3N)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
FAAH O00519 3/20 0.44
THRB P10828 1/20 0.42
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1680924 0.97 SMN1; SMN2 (0.50) SMN1; SMN2LMNAFAAHTHRBHPGD
SCHEMBL920594 0.96 TSHR (0.44) SMN1; SMN2LMNAFAAHHPGDEGLN1
SCHEMBL922948 0.93 FAAH (0.42) SMN1; SMN2LMNAFAAHEGLN1
SCHEMBL920800 0.92 LMNA (0.40) SMN1; SMN2LMNAHPGDEGLN1
SCHEMBL922173 0.92 POLB (0.48) SMN1; SMN2LMNAHPGDEGLN1POLB
SCHEMBL921603 0.91 TRPV1 (0.42) SMN1; SMN2LMNAHPGDEGLN1
SCHEMBL920715 0.90 EGLN1 (0.40) SMN1; SMN2LMNAHPGDEGLN1
SCHEMBL920018 0.90 TP53 (0.41) SMN1; SMN2LMNAHPGDEGLN1POLB
SCHEMBL920520 0.90 CARM1 (0.44) SMN1; SMN2LMNAFAAHHPGDEGLN1
SCHEMBL921335 0.89 HDAC1 (0.44) SMN1; SMN2LMNAHPGDEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 SMN1; SMN2 4796/4885LMNA 4812/4885FAAH 4388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.