Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571905 | 0.81 | LMNA (0.42) | CYP2D6LMNATDP1TAAR1SLC6A2 | |
| SCHEMBL29648088 | 0.76 | CYP2D6 (0.59) | CYP2D6LMNASIGMAR1HTR1ASCN1A | |
| SCHEMBL6497301 | 0.71 | TSHR (0.43) | CYP2D6LMNATAAR1SLC6A2ALDH1A1 | |
| SCHEMBL11328818 | 0.70 | KCNN4 (0.44) | CYP2D6LMNASIGMAR1HTR1ASCN1A | |
| SCHEMBL4658121 | 0.70 | ALDH1A1 (0.55) | CYP2D6LMNATAAR1ALDH1A1RECQL | |
| SCHEMBL9583515 | 0.70 | SLC6A2 (0.46) | CYP2D6LMNASIGMAR1HTR1ASCN1A | |
| SCHEMBL7959025 | 0.69 | MEN1 (0.57) | LMNAPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL9583860 | 0.69 | SLC6A2 (0.44) | CYP2D6LMNASIGMAR1TAAR1SLC6A2 | |
| SCHEMBL11252135 | 0.68 | SMN1; SMN2 (0.40) | CYP2D6LMNAHTR1ASCN1ASLC6A3 | |
| SCHEMBL5088767 | 0.68 | SLC6A2 (0.50) | CYP2D6LMNATAAR1SLC6A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382618-B1 | Aminoalkoxyphenyl derivatives, process for their preparation and compositions containing them | SANOFI SA (FR) | 1995-09-20 | — | — | EP | disclosed |
| EP-0382618-A2 | Aminoalkoxyphenyl derivatives, process for their preparation and compositions containing them | SANOFI (FR) | 1990-08-16 | — | — | EP | disclosed |