Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 17/20 | 0.67 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209676 | 0.84 | AOC3 (0.69) | MALT1AOC3EPHX2 | |
| SCHEMBL9201624 | 0.83 | PTGS2 (0.47) | MALT1AOC3RXRARXRBRXRG | |
| SCHEMBL9203794 | 0.81 | PTGS2 (0.48) | MALT1RXRARXRBRXRG | |
| SCHEMBL9205227 | 0.80 | PTGS2 (0.51) | MALT1RXRARXRBRXRG | |
| SCHEMBL9208424 | 0.80 | PTGS2 (0.49) | RXRARXRBRXRG | |
| SCHEMBL9211086 | 0.78 | PTGS2 (0.45) | MALT1RXRARXRBRXRG | |
| SCHEMBL9204658 | 0.77 | KMT2A (0.72) | — | |
| SCHEMBL9204760 | 0.77 | KMT2A (0.72) | — | |
| SCHEMBL3865146 | 0.76 | PTGS2 (0.69) | MALT1AOC3 | |
| SCHEMBL9209766 | 0.76 | MEN1 (0.56) | MALT1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418845-B1 | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0418845-A1 | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-27 | — | — | EP | disclosed |