SCHEMBL920882

SCHEMBL920882

Cc1ccccc1Oc1ccc(CNC(=O)c2cccnc2N)s1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.47
ADORA2A P29274 4/20 0.41
ADORA1 P30542 3/20 0.41
ADORA3 P0DMS8 1/20 0.41
ADORA2B P29275 1/20 0.41
PRKCI P41743 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 2/20 0.41
MAPK14 Q16539 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 2/20 0.40
MAPK8 P45983 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
MAPK1 P28482 1/20 0.40
PDPK1 O15530 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1680737 0.88 ALDH1A1 (0.46) PIK3CDPRKCIL3MBTL1MAPK14MEN1
SCHEMBL1680415 0.85 MAPK8 (0.52) PIK3CDPRKCIMAPK14KDM4EMAPK8
SCHEMBL1680807 0.84 GAA (0.49) PIK3CDMAPTMAPK14MEN1KMT2A
SCHEMBL1680602 0.82 KMT2A (0.44) PIK3CDMAPK14KMT2AMAPK8PDPK1
SCHEMBL1681019 0.82 PIK3CD (0.42) PIK3CDMAPTMEN1KMT2AKDM4E
SCHEMBL1680603 0.80 POLB (0.45) PIK3CDL3MBTL1MAPK14KDM4EMAPK8
SCHEMBL919966 0.80 MAPK14 (0.61) PIK3CDL3MBTL1MAPTMAPK14MEN1
SCHEMBL1680915 0.78 MAPK8 (0.40) PIK3CDPRKCIMAPTMEN1KMT2A
SCHEMBL1680815 0.78 PDPK1 (0.41) PIK3CDADORA2AADORA1KMT2AMAPK8
SCHEMBL1680652 0.78 PDPK1 (0.44) PIK3CDMAPK8ALDH1A1HPGDPDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 PIK3CD 3892/4885ADORA2A 4433/4885ADORA1 3433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.