SCHEMBL1680807

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680415	0.90	MAPK8 (0.52)	PIK3CDALDH1A1MAPK8KDM4EMAPK14
	SCHEMBL1680602	0.90	KMT2A (0.44)	PIK3CDMAPK8CYP3A4KMT2AMAPK14
	SCHEMBL1680603	0.90	POLB (0.45)	GAAHPGDPIK3CDALDH1A1MAPK8
	SCHEMBL1681019	0.89	PIK3CD (0.42)	GAAHPGDPIK3CDALDH1A1MAPK8
	SCHEMBL920882	0.84	PIK3CD (0.47)	HPGDPIK3CDALDH1A1MAPK8MAPK1
	SCHEMBL921783	0.84	MMP13 (0.38)	GAAHPGDMMP13ALDH1A1SMN1; SMN2
	SCHEMBL1680915	0.83	MAPK8 (0.40)	HPGDPIK3CDALDH1A1MAPK8MAPT
	SCHEMBL1680652	0.83	PDPK1 (0.44)	GAAHPGDPIK3CDALDH1A1MAPK8
	SCHEMBL1680815	0.83	PDPK1 (0.41)	HPGDPIK3CDMAPK8KMT2A
	SCHEMBL922484	0.82	HPGD (0.62)	GAAHPGDMMP13ALDH1A1MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.