SCHEMBL920906

SCHEMBL920906

Cc1ccc(C(=O)NCc2ccc(Oc3ccccc3Br)cc2)c(N)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.47
ALDH1A1 P00352 2/20 0.47
GAA P10253 1/20 0.47
HTT P42858 1/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPK14 Q16539 3/20 0.46
CARM1 Q86X55 2/20 0.43
PRMT6 Q96LA8 2/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ADORA2A P29274 2/20 0.42
ADORA1 P30542 1/20 0.42
GALR3 O60755 1/20 0.42
NR2F2 P24468 1/20 0.42
TP53 P04637 2/20 0.41
RXFP1 Q9HBX9 1/20 0.41
GLA P06280 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921442 0.89 MAPK14 (0.58) HPGDALDH1A1GAAHTTATM
SCHEMBL920667 0.89 HPGD (0.48) HPGDALDH1A1CA2CA4KDM4E
SCHEMBL920313 0.88 CARM1 (0.55) HPGDALDH1A1GAAHTTATM
SCHEMBL922269 0.88 HTT (0.47) HPGDALDH1A1GAAHTTATM
SCHEMBL920517 0.88 ALDH1A1 (0.47) HPGDALDH1A1GAAHTTATM
SCHEMBL921214 0.88 HPGD (0.47) HPGDALDH1A1GAAHTTATM
SCHEMBL921254 0.88 MAPK14 (0.56) HPGDALDH1A1GAAHTTATM
SCHEMBL922229 0.88 HPGD (0.47) HPGDALDH1A1GAAHTTATM
SCHEMBL919964 0.87 MAPK14 (0.57) HPGDALDH1A1GAAHTTATM
SCHEMBL921942 0.87 HPGD (0.46) HPGDALDH1A1GAAHTTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885ALDH1A1 2743/4885GAA 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.