SCHEMBL922229

SCHEMBL922229

Nc1nc(F)ccc1C(=O)NCc1ccc(Oc2ccccc2Br)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
HTT P42858 1/20 0.47
ATM Q13315 1/20 0.47
PTGER4 P35408 3/20 0.45
PTGER2 P43116 1/20 0.45
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
GALR3 O60755 1/20 0.42
NR2F2 P24468 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
MAPK14 Q16539 3/20 0.41
KMT2A Q03164 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
CARM1 Q86X55 1/20 0.41
PRMT6 Q96LA8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921057 0.89 L3MBTL1 (0.48) HPGDL3MBTL1ALDH1A1GAAHTT
SCHEMBL920829 0.89 HPGD (0.46) HPGDL3MBTL1ALDH1A1GAAHTT
SCHEMBL922774 0.88 L3MBTL1 (0.47) HPGDL3MBTL1ALDH1A1GAAHTT
SCHEMBL920906 0.88 HPGD (0.47) HPGDL3MBTL1ALDH1A1GAAHTT
SCHEMBL919884 0.88 CARM1 (0.54) HPGDL3MBTL1ALDH1A1GAAHTT
SCHEMBL922161 0.88 MAPK14 (0.56) HPGDL3MBTL1ALDH1A1GAAHTT
SCHEMBL921103 0.88 MAPK14 (0.56) HPGDL3MBTL1ALDH1A1GAAHTT
SCHEMBL921469 0.87 MAPK14 (0.52) HPGDL3MBTL1ALDH1A1GAAHTT
SCHEMBL921932 0.87 HTT (0.46) HPGDL3MBTL1ALDH1A1GAAHTT
SCHEMBL921586 0.87 L3MBTL1 (0.46) HPGDL3MBTL1ALDH1A1GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885L3MBTL1 1292/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.