Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217236 | 0.76 | TLR7 (0.43) | TLR7KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL9215234 | 0.76 | TLR7 (0.64) | ADORA3TLR7ATMKMT2ACNR2 | |
| SCHEMBL9216421 | 0.73 | TLR7 (0.54) | ADORA3TLR7ATMKMT2APOLB | |
| SCHEMBL11915890 | 0.71 | ADORA3 (0.64) | ADORA3TLR7ADORA2A | |
| SCHEMBL12791633 | 0.69 | TAAR1 (0.61) | TLR7KMT2AUSP2POLBCNR2 | |
| SCHEMBL13196912 | 0.68 | TLR7 (0.62) | TLR7ATMKMT2AUSP2POLB | |
| SCHEMBL2708712 | 0.68 | TLR7 (0.47) | ADORA3TLR7ATMALDH1A1 | |
| SCHEMBL9212191 | 0.68 | LMNA (0.50) | ADORA3KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL9218507 | 0.67 | IKBKB (0.46) | TLR7POLBKDM4EHSD17B10ADORA2A | |
| SCHEMBL9209184 | 0.67 | ALDH1A1 (0.51) | TLR7KMT2APOLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386722-B1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-4994468-A | Bronchodilators, antiallergens | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0386722-A1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |