Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216421 | 0.81 | TLR7 (0.54) | ALDH1A1PKMKDM4EHPGDALOX15 | |
| SCHEMBL9217236 | 0.78 | TLR7 (0.43) | LMNAALDH1A1TSHRKDM4EMAPT | |
| SCHEMBL9212879 | 0.76 | ALDH1A1 (0.52) | LMNAHIF1ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL9209184 | 0.73 | ALDH1A1 (0.51) | LMNAALDH1A1TSHRKDM4EMAPT | |
| SCHEMBL25397383 | 0.71 | LMNA (0.40) | LMNAHIF1ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4622963 | 0.70 | ALDH1A1 (0.70) | LMNAHIF1ASMN1; SMN2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL11178082 | 0.69 | ALDH1A1 (0.57) | LMNAHIF1ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL503307 | 0.68 | MEN1 (0.75) | LMNAALDH1A1TSHRPKMKDM4E | |
| SCHEMBL9209642 | 0.68 | ADORA3 (0.56) | ALDH1A1KDM4EHSD17B10MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL9214677 | 0.67 | ALDH1A1 (0.59) | LMNAHIF1ASMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386722-B1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-4994468-A | Bronchodilators, antiallergens | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0386722-A1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |