Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21625271 | 0.94 | SIGMAR1 (0.49) | SIGMAR1L3MBTL1MAOA | |
| SCHEMBL23531244 | 0.86 | TSHR (0.48) | MEN1KMT2A | |
| SCHEMBL919366 | 0.86 | TSHR (0.48) | MEN1KMT2A | |
| SCHEMBL19090603 | 0.82 | SIGMAR1 (0.50) | SIGMAR1L3MBTL1MEN1KMT2AMAOA | |
| SCHEMBL108633 | 0.82 | LMNA (0.54) | SIGMAR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30514257 | 0.80 | LMNA (0.53) | SIGMAR1MEN1KMT2A | |
| SCHEMBL4423916 | 0.79 | SIGMAR1 (0.44) | SIGMAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL10473337 | 0.78 | GRIK1 (0.54) | MEN1KMT2A | |
| SCHEMBL9244748 | 0.78 | SIGMAR1 (0.45) | SIGMAR1MAOA | |
| SCHEMBL1678945 | 0.78 | GRIK1 (0.54) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131692-A1 | SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2009-10-29 | — | — | WO | claimed |
| US-5631401-A | Inhibitors of protein farnesyltransferase and squalene synthase | ABBOTT LABORATORIES (US) | 1997-05-20 | — | — | US | claimed |
| WO-1995021815-A1 | CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND SQUALENE SYNTHASE | ABBOTT LABORATORIES (US) | 1995-08-17 | — | — | WO | claimed |
| CN-107614477-B | Compound, latent additive and composition containing the additive | 株式会社艾迪科 | 2021-08-24 | — | — | CN | disclosed |
| CN-113166070-A | Pesticidal compounds | 巴斯夫欧洲公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-109694454-A | Preparation method of block copolymer and monovinylarene-isomonoolefin-monovinylarene block copolymer | 中国石油化工股份有限公司 | 2019-04-30 | — | — | CN | disclosed |
| CN-109694453-A | Preparation method of block copolymer and monovinylarene-isomonoolefin-monovinylarene block copolymer | 中国石油化工股份有限公司 | 2019-04-30 | — | — | CN | disclosed |
| EP-2226632-B1 | METHOD FOR SCREENING OF CELL-PROTECTING AGENT | TAKEDA PHARMACEUTICAL (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-8450070-B2 | Method for screening of cell-protecting agent | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-05-28 | — | — | US | disclosed |
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2345328-A1 | COMPOSITION FOR AGRICULTURAL USE | Sumitomo Chemical Company, Limited (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-4316901-A | Animal feed and process | THE UPJOHN COMPANY (US) | 1982-02-23 | — | — | US | disclosed |
| US-4315930-A | A DIAMINO-TRIAZINE-3-OXIDE | THE UPJOHN COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| EP-0042669-A2 | Compounds and compositions for use in animal feeds | THE UPJOHN COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4308271-A | PYRIMIDINE OXIDE DERIVATIVES TO INCREASE PRODUCTION | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4307093-A | INCREASING PRODUCTION USING OXATRIAZINES | THE UPJOHN COMPANY (US) | 1981-12-22 | — | — | US | disclosed |
| US-4282228-A | Animal feed and process | THE UPJOHN COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4089672-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
| US-4084955-A | 1-CARBOXYALKYL-DI- AND TRIHALOPYRAZOLES, HERBICIDES | THE UPJOHN COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-3998827-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | H1-0, H1-3, H1-2 | SIGMAR1 3290/4885L3MBTL1 779/4885MEN1 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.