Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209063 | 0.85 | PDK1 (0.45) | PDK1ALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL9213963 | 0.79 | ALDH1A1 (0.43) | PDK1ALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL9217634 | 0.74 | POLB (0.38) | PDK1ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL9456218 | 0.70 | ALDH1A1 (0.38) | PDK1ALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL9207952 | 0.70 | POLB (0.34) | PDK1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL1002931 | 0.69 | PDK1 (0.73) | PDK1ALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL9208015 | 0.69 | PDK1 (0.63) | PDK1ALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL9219349 | 0.69 | HTR1A (0.42) | PDK1ALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL9275611 | 0.69 | PDK1 (0.58) | PDK1ALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL9214665 | 0.69 | MAPT (0.63) | PDK1ALDH1A1SMN1; SMN2RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |