Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217634 | 0.86 | POLB (0.38) | POLBNPC1PDK1RAB9ASMN1; SMN2 | |
| SCHEMBL9209880 | 0.82 | HTR1A (0.41) | SMN1; SMN2 | |
| SCHEMBL9209770 | 0.77 | NPC1 (0.50) | POLBNPC1PDK1RAB9ASMN1; SMN2 | |
| SCHEMBL9209063 | 0.77 | PDK1 (0.45) | POLBNPC1PDK1RAB9ASMN1; SMN2 | |
| SCHEMBL9456218 | 0.75 | ALDH1A1 (0.38) | POLBNPC1PDK1RAB9ASMN1; SMN2 | |
| SCHEMBL9207415 | 0.75 | DRD2 (0.38) | POLBNPC1PDK1 | |
| SCHEMBL9210123 | 0.72 | PDK1 (0.44) | POLBNPC1PDK1RAB9ASMN1; SMN2 | |
| SCHEMBL9217319 | 0.71 | POLB (0.43) | POLBNPC1PDK1RAB9ASMN1; SMN2 | |
| SCHEMBL9209984 | 0.70 | PDK1 (0.50) | POLBNPC1PDK1RAB9ASMN1; SMN2 | |
| SCHEMBL9218091 | 0.69 | ALDH1A1 (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | claimed |
| EP-0405976-A1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-02 | — | — | EP | claimed |
| EP-0684945-A1 | HETEROCYCLIC-SUBSTITUTED ALKYL AMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |