Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211673 | 0.85 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL9211317 | 0.79 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL9205436 | 0.79 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL9213586 | 0.78 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL9210124 | 0.77 | GRM2 (0.51) | — | |
| SCHEMBL9205405 | 0.76 | LMNA (0.38) | ALDH1A1 | |
| SCHEMBL9208921 | 0.75 | HTR1A (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL9208097 | 0.75 | MCHR1 (0.40) | — | |
| SCHEMBL9211907 | 0.74 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HDAC6 | |
| SCHEMBL9211887 | 0.74 | MIF (0.34) | SLC6A2SLC6A4SLC6A3ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |