Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 10/20 | 0.36 |
| ▸ | CA2 | P00918 | 9/20 | 0.36 |
| ▸ | CA4 | P22748 | 8/20 | 0.36 |
| ▸ | CA7 | P43166 | 8/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211673 | 0.84 | SLC6A2 (0.44) | ALDH1A1 | |
| SCHEMBL9211643 | 0.82 | MIF (0.34) | ALDH1A1 | |
| SCHEMBL9208921 | 0.81 | HTR1A (0.42) | CA1CA4CA7CA12CA9 | |
| SCHEMBL9210057 | 0.81 | CA12 (0.39) | LMNACA1CA4CA7CA12 | |
| SCHEMBL9214055 | 0.79 | MIF (0.34) | — | |
| SCHEMBL9205394 | 0.79 | GRM2 (0.45) | CA2 | |
| SCHEMBL9204689 | 0.76 | ALOX5 (0.44) | ALOX5CA1CA2CA4CA7 | |
| SCHEMBL9209400 | 0.76 | ALOX5 (0.44) | ALOX5CA1CA2CA4CA7 | |
| SCHEMBL9206290 | 0.76 | HRH3 (0.33) | LMNA | |
| SCHEMBL9210131 | 0.76 | SLC6A2 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |