Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208921 | 0.89 | HTR1A (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL9206576 | 0.88 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3OPRM1KCNH2 | |
| SCHEMBL9204457 | 0.88 | MIF (0.34) | SLC6A2SLC6A4SLC6A3OPRM1KCNH2 | |
| SCHEMBL9211643 | 0.88 | MIF (0.34) | SLC6A2SLC6A4SLC6A3OPRM1KCNH2 | |
| SCHEMBL9211887 | 0.88 | MIF (0.34) | SLC6A2SLC6A4SLC6A3OPRM1KCNH2 | |
| SCHEMBL9214055 | 0.86 | MIF (0.34) | SLC6A2SLC6A4SLC6A3OPRM1KCNH2 | |
| SCHEMBL9215789 | 0.85 | ALOX5 (0.44) | KCNH2ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL9204689 | 0.85 | ALOX5 (0.44) | KCNH2ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL9209400 | 0.85 | ALOX5 (0.44) | KCNH2ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL9210131 | 0.85 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3218367-A | — | — | None | — | — | JP | disclosed |
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| JP-H03218367-A | NAPHTHYLOXAZOLIDONE DERIVATIVE, ITS PRODUCTION AND INTERMEDIATE FOR SYNTHESIZING THE SAME | TANABE SEIYAKU CO LTD | 1991-09-25 | — | — | JP | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |