Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210229 | 1.00 | IMPDH2 (0.35) | IMPDH2IMPDH1KDM4EALDH1A1HPGD | |
| SCHEMBL9207927 | 0.85 | KDM4E (0.30) | KDM4EALDH1A1HPGD | |
| SCHEMBL9200073 | 0.84 | — | — | |
| SCHEMBL9200081 | 0.84 | — | — | |
| SCHEMBL9851204 | 0.83 | MEN1 (0.37) | IMPDH2IMPDH1 | |
| SCHEMBL9210153 | 0.80 | ALOX5 (0.42) | — | |
| SCHEMBL8136061 | 0.80 | ALOX5 (0.42) | — | |
| SCHEMBL9208447 | 0.79 | THRA (0.41) | IMPDH2IMPDH1KDM4EALDH1A1HPGD | |
| SCHEMBL9201963 | 0.78 | PTPN1 (0.38) | — | |
| SCHEMBL9201691 | 0.71 | MEN1 (0.37) | IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413668-B1 | New 2,3-dihydro-5-oxy-4,6,7-trimethylbenzofuranes 2-(RS)-substitutes, useful as antioxidizing pharmaceutical products having mucoregolating and anti-ischemic properties | FOSCAMA BIOMED CHIM FARMA (IT) | 1995-12-06 | — | — | EP | disclosed |
| US-5114966-A | Radical scavengers | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1992-05-19 | — | — | US | disclosed |