Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 12/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Raxofelast SCHEMBL633619 | 0.86 | THRA (0.40) | THRATHRBIMPDH2IMPDH1KDM4E | |
| Raxofelast SCHEMBL633620 | 0.86 | THRA (0.40) | THRATHRBIMPDH2IMPDH1KDM4E | |
| SCHEMBL7108510 | 0.81 | PSEN1 (0.52) | THRATHRB | |
| SCHEMBL6885035 | 0.81 | TSHR (0.39) | THRATHRBMIFCYP1A2CYP3A4 | |
| SCHEMBL29842394 | 0.81 | TSHR (0.39) | THRATHRBMIFCYP1A2CYP3A4 | |
| SCHEMBL9210219 | 0.79 | IMPDH2 (0.35) | IMPDH2IMPDH1KDM4EHPGDALDH1A1 | |
| SCHEMBL9210229 | 0.79 | IMPDH2 (0.35) | IMPDH2IMPDH1KDM4EHPGDALDH1A1 | |
| SCHEMBL9207927 | 0.77 | KDM4E (0.30) | KDM4EHPGDALDH1A1 | |
| SCHEMBL9210119 | 0.75 | THRA (0.34) | THRATHRBMIFKDM4E | |
| SCHEMBL9786760 | 0.74 | MEN1 (0.36) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413668-B1 | New 2,3-dihydro-5-oxy-4,6,7-trimethylbenzofuranes 2-(RS)-substitutes, useful as antioxidizing pharmaceutical products having mucoregolating and anti-ischemic properties | FOSCAMA BIOMED CHIM FARMA (IT) | 1995-12-06 | — | — | EP | disclosed |
| US-5114966-A | Radical scavengers | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1992-05-19 | — | — | US | disclosed |