Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011216 | 0.73 | PNMT (0.44) | PNMTTSHR | |
| SCHEMBL2307452 | 0.67 | PRCP (0.50) | MEN1CYP2C19KMT2AGID4 | |
| SCHEMBL5741125 | 0.67 | TSHR (0.45) | PNMTTSHR | |
| SCHEMBL13881344 | 0.64 | PNMT (0.50) | PNMT | |
| SCHEMBL12644551 | 0.63 | TAAR1 (0.46) | PNMTMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL2845448 | 0.62 | KDM4E (0.38) | PNMTMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL12563257 | 0.62 | PNMT (0.56) | PNMTMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL8028673 | 0.62 | MAOA (0.45) | PNMTMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL14906789 | 0.59 | PNMT (0.37) | PNMTMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL13303498 | 0.59 | UGT2B17 (0.47) | PNMTMEN1TSHRCYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333427-B1 | Heterocyclic derivatives | SMITHKLINE BEECHAM FARMA (IT) | 1995-08-23 | — | — | EP | claimed |