SCHEMBL921070

SCHEMBL921070

Cc1ccc(C(=O)NCc2ccc(Oc3cccc(F)c3)cc2)c(N)n1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GCK P35557 2/20 0.48
HTR2C P28335 1/20 0.48
HTR2B P41595 1/20 0.48
KLKB1 P03952 4/20 0.47
MAPK14 Q16539 1/20 0.45
PTGER4 P35408 2/20 0.44
PTGER2 P43116 1/20 0.44
LIPG Q9Y5X9 1/20 0.44
SCN9A Q15858 1/20 0.44
CHRM4 P08173 1/20 0.44
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAPT P10636 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919651 0.93 MAPT (0.50) GCKKLKB1CHRM4MAPT
SCHEMBL921861 0.90 MMP13 (0.48) GCKMAPK14CHRM4MAPT
SCHEMBL919925 0.90 HTR2C (0.49) GCKHTR2CHTR2BKLKB1MAPK14
SCHEMBL920420 0.90 MAPK14 (0.49) KLKB1MAPK14CHRM4HTTSMN1; SMN2
SCHEMBL920459 0.89 LIPG (0.55) MAPK14PTGER4PTGER2LIPGSCN9A
SCHEMBL920890 0.89 MMP13 (0.52) KLKB1MAPK14CHRM4ADORA2AADORA1
SCHEMBL919964 0.88 MAPK14 (0.57) KLKB1MAPK14LIPGHTTSMN1; SMN2
SCHEMBL919767 0.88 MMP13 (0.46) KLKB1MAPK14CHRM4
SCHEMBL920516 0.88 MAPK14 (0.45) KLKB1MAPK14CHRM4HTTSMN1; SMN2
SCHEMBL922346 0.88 KLKB1 (0.49) KLKB1MAPK14HTTADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 GCK 594/4885HTR2C 4348/4885HTR2B 4807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.