SCHEMBL922484

SCHEMBL922484

Cc1ccc(Oc2ccc(CNC(=O)c3cccnc3N)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.62
KDM4E B2RXH2 1/20 0.57
ALDH1A1 P00352 1/20 0.57
MAPK14 Q16539 2/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
MMP13 P45452 2/20 0.56
CYP3A4 P08684 2/20 0.56
MMP2 P08253 1/20 0.56
STAT3 P40763 1/20 0.56
HTT P42858 1/20 0.56
MAPK8 P45983 1/20 0.55
GAA P10253 1/20 0.55
LMNA P02545 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
POLB P06746 2/20 0.50
EGLN1 Q9GZT9 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920122 0.93 HPGD (0.68) HPGDKDM4EALDH1A1SMN1; SMN2CYP3A4
SCHEMBL922349 0.92 HPGD (0.53) HPGDKDM4EALDH1A1MAPK14SMN1; SMN2
SCHEMBL922511 0.91 HPGD (0.60) HPGDKDM4EALDH1A1SMN1; SMN2CYP3A4
SCHEMBL921037 0.91 HPGD (0.66) HPGDALDH1A1SMN1; SMN2MAPK8LMNA
SCHEMBL920473 0.91 HPGD (0.57) HPGDALDH1A1SMN1; SMN2MAPK8LMNA
SCHEMBL920461 0.90 MAPK8 (0.67) HPGDALDH1A1MAPK14SMN1; SMN2MMP13
SCHEMBL920714 0.90 MAPK8 (0.53) HPGDKDM4EALDH1A1MAPK14SMN1; SMN2
SCHEMBL921092 0.90 MMP13 (0.58) HPGDKDM4EALDH1A1MAPK14MMP13
SCHEMBL920793 0.89 LMNA (0.61) HPGDKDM4ESMN1; SMN2MAPK8LMNA
SCHEMBL921056 0.89 LMNA (0.57) HPGDSMN1; SMN2MAPK8LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885KDM4E 3657/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.