Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211887 | 1.00 | MIF (0.34) | MIFSLC6A2SLC6A4SLC6A3ESR1 | |
| SCHEMBL9204457 | 1.00 | MIF (0.34) | MIFSLC6A2SLC6A4SLC6A3ESR1 | |
| SCHEMBL9214055 | 0.96 | MIF (0.34) | MIFSLC6A2SLC6A4SLC6A3ESR1 | |
| SCHEMBL9211673 | 0.88 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3OPRM1KCNH2 | |
| SCHEMBL9208921 | 0.84 | HTR1A (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1MEN1 | |
| SCHEMBL9210057 | 0.83 | CA12 (0.39) | ABL1ALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL9206576 | 0.83 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3OPRM1KCNH2 | |
| SCHEMBL9205405 | 0.82 | LMNA (0.38) | ALDH1A1 | |
| SCHEMBL9205120 | 0.81 | BACE1 (0.40) | SLC6A2SLC6A4SLC6A3KCNH2RAB9A | |
| SCHEMBL8566875 | 0.81 | BACE1 (0.40) | SLC6A2SLC6A4SLC6A3KCNH2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |