Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NAAA | Q02083 | 2/20 | 0.53 |
| ▸ | MAP2 | P11137 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276134 | 0.81 | USP2 (0.61) | GAAUSP2KDM4EALDH1A1HPGD | |
| SCHEMBL6353285 | 0.79 | GAA (0.72) | GAAKDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL24073027 | 0.79 | GAA (0.60) | GAAKDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL24073014 | 0.79 | GAA (0.60) | GAAKDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL7566685 | 0.77 | GAA (1.00) | GAAKDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL7566792 | 0.77 | GAA (0.57) | GAAKDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL7529957 | 0.77 | GAA (0.57) | GAAKDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL4926259 | 0.76 | ALDH1A1 (0.56) | GAAKDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL2760046 | 0.76 | MAP2 (0.59) | GAAKDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL9218552 | 0.76 | NAAA (0.53) | USP2ALDH1A1NAAAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |