Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12922067 | 0.76 | HDAC1 (0.62) | ALOX15PTGS2RAB9AALDH1A1 | |
| SCHEMBL9212419 | 0.76 | GAA (0.62) | NAAAALOX15USP2RAB9AALDH1A1 | |
| SCHEMBL9209956 | 0.73 | PTPN1 (0.51) | HTT | |
| SCHEMBL9212465 | 0.73 | HDAC1 (0.54) | NAAAALOX15RAB9AEPHX1ALDH1A1 | |
| SCHEMBL2506707 | 0.72 | LMNA (0.49) | ALOX15RAB9AALDH1A1HTT | |
| SCHEMBL6360786 | 0.72 | PTGS2 (0.51) | ALOX15PTGS2RAB9AALDH1A1 | |
| SCHEMBL11601813 | 0.72 | CNR2 (0.53) | — | |
| SCHEMBL2958622 | 0.72 | MCL1 (0.61) | ALOX15PTGS2ALDH1A1 | |
| SCHEMBL975593 | 0.72 | LMNA (0.69) | ALOX15ALDH1A1 | |
| SCHEMBL1002305 | 0.71 | NAAA (1.00) | NAAARAB9AEPHX1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |