Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219294 | 0.84 | NAAA (0.50) | NAAAHPGDALDH1A1HTTL3MBTL1 | |
| SCHEMBL9219330 | 0.79 | NAAA (0.50) | NAAAHPGDALDH1A1HTTL3MBTL1 | |
| SCHEMBL9211979 | 0.77 | ALDH1A1 (0.43) | NAAAHPGDALDH1A1HTTL3MBTL1 | |
| SCHEMBL1286894 | 0.76 | NAAA (0.67) | NAAAHPGDHTTTSHRMAPK1 | |
| SCHEMBL3238026 | 0.76 | NAAA (0.67) | NAAAHPGDHTTTSHRMAPK1 | |
| SCHEMBL27801490 | 0.76 | NAAA (0.67) | NAAAHPGDHTTTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL13738790 | 0.76 | MMP13 (0.59) | HPGDALDH1A1L3MBTL1KDM4EGLA | |
| SCHEMBL14058606 | 0.74 | TSHR (0.66) | NAAAHPGDHTTTSHR | |
| SCHEMBL11331402 | 0.74 | NAAA (0.63) | NAAAHPGDALDH1A1HTTL3MBTL1 | |
| SCHEMBL11113919 | 0.74 | NAAA (0.63) | NAAAHPGDALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |